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Our lab investigates human memory and its neural basis utilizing a mixture of behavioral, computational, and neurophysiological methods. In our computational investigations, we build mathematical and laptop-simulation fashions to account for the dynamics of memory retrieval in a wide range of episodic and spatial memory duties. Because behavioral knowledge supplies a sparse reflection of the brain’s activity supporting memory, we simultaneously file neurophysiological signals as patients with arrays of implanted electrodes carry out memory tasks. In these investigations we examine neural exercise at a number of spatial scales, ranging from individual neurons to spatially-distributed networks of discipline-potential activity supporting memory. A number of of our current projects also use electrical stimulation to control memory circuits, each for understanding basic memory mechanisms and also for developing therapies to revive memory in patients with brain harm or neurological illness. Please click right here for more data and errata. To assist explain the processes underlying encoding, organization and retrieval of episodic reminiscences, we have developed, prolonged and refined a class of models primarily based on the idea that objects in memory develop into related to a time-varying representation of spatio-temporal context.

The temporal context mannequin (TCM